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rnh-1.1 ribonuclease H [ Caenorhabditis elegans ]

Gene ID: 174222, updated on 2-Nov-2024

Summary

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Official Symbol
rnh-1.1
Official Full Name
ribonuclease H
Primary source
WormBase:WBGene00022888
Locus tag
CELE_ZK1290.6
See related
AllianceGenome:WB:WBGene00022888
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables RNA-DNA hybrid ribonuclease activity. Predicted to be involved in DNA replication, removal of RNA primer. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See rnh-1.1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
17
Sequence:
Chromosome: II; NC_003280.10 (7525738..7528239)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene putative oxidoreductase ZK1290.5

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Multiple ribonuclease H-encoding genes in the Caenorhabditis elegans genome contrasts with the two typical ribonuclease H-encoding genes in the human genome. Arudchandran A, et al. Mol Biol Evol, 2002 Nov. PMID 12411600
  2. Stage-specific expression of Caenorhabditis elegans ribonuclease H1 enzymes with different substrate specificities and bivalent cation requirements. Kochiwa H, et al. FEBS J, 2006 Jan. PMID 16403028
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables RNA-DNA hybrid ribonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA-DNA hybrid ribonuclease activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables RNA-DNA hybrid ribonuclease activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in DNA replication, removal of RNA primer IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in nucleic acid metabolic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ribonuclease H
NP_001022508.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    7525738..7528239
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001027337.4 → NP_001022508.1  ribonuclease H [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022508.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q09633
    Conserved Domains (1) summary
    cd09280
    Location:328 → 457
    RNase_HI_eukaryote_like; Eukaryotic RNase H is essential and is longer and more complex than their prokaryotic counterparts
Nucleotide Protein
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