decr-1.3 putative 2,4-dienoyl-CoA reductase 3 [(3E)-enoyl-CoA-producing] [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: decr-1.3
Official Full Name: putative 2,4-dienoyl-CoA reductase 3 [(3E)-enoyl-CoA-producing]
Primary source: WormBase:WBGene00011467
Locus tag: CELE_T05C12.3
See related: AllianceGenome:WB:WBGene00011467
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable 2,4-dienoyl-CoA reductase (NADPH) activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be active in mitochondrion. Orthologous to human DECR1 (2,4-dienoyl-CoA reductase 1). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See decr-1.3 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 5

Sequence:: Chromosome: II; NC_003280.10 (8172229..8173549, complement)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

T05C12.1 (e-PCR)
- UniSTS:307921

T05C12.3 (e-PCR)
- UniSTS:307923

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables 2,4-dienoyl-CoA reductase (NADPH) activity	IBA Inferred from Biological aspect of Ancestor more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in fatty acid beta-oxidation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: putative 2,4-dienoyl-CoA reductase 3 [(3E)-enoyl-CoA-producing]

NP_495714.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

8172229..8173549 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_063313.3 → NP_495714.1 putative 2,4-dienoyl-CoA reductase 3 [(3E)-enoyl-CoA-producing] [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_495714.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q22230

Conserved Domains (2) summary

PRK07677
Location:25 → 272

PRK07677; short chain dehydrogenase; Provisional

cd05369
Location:23 → 274

TER_DECR_SDR_a; Trans-2-enoyl-CoA reductase (TER) and 2,4-dienoyl-CoA reductase (DECR), atypical (a) SDR