U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

chmp-7 Charged multivesicular body protein 7 [ Caenorhabditis elegans ]

Gene ID: 174442, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
chmp-7
Official Full Name
Charged multivesicular body protein 7
Primary source
WormBase:WBGene00011976
Locus tag
CELE_T24B8.2
See related
AllianceGenome:WB:WBGene00011976
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in late endosome to vacuole transport via multivesicular body sorting pathway and vesicle budding from membrane. Predicted to be part of ESCRT III complex. Predicted to be active in cytoplasmic side of plasma membrane and multivesicular body. Orthologous to human CHMP7 (charged multivesicular body protein 7). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See chmp-7 in Genome Data Viewer
Location:
chromosome: II
Exon count:
4
Sequence:
Chromosome: II; NC_003280.10 (9054972..9056504)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene UBA domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 60S ribosomal protein L32;Large ribosomal subunit protein eL32 Neighboring gene ncRNA Neighboring gene Prothymosin alpha Neighboring gene ncRNA

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Nuclear envelope assembly relies on CHMP-7 in the absence of BAF-LEM-mediated hole closure. Barger SR, et al. J Cell Sci, 2023 Nov 1. PMID 37795681, Free PMC Article
  2. The ESCRT machinery directs quality control over inner nuclear membrane architecture. Shankar R, et al. Cell Rep, 2022 Jan 18. PMID 35045304, Free PMC Article
  3. A membrane reticulum, the centriculum, affects centrosome size and function in Caenorhabditis elegans. Maheshwari R, et al. Curr Biol, 2023 Mar 13. PMID 36693370, Free PMC Article
  4. Roles for the RNA polymerase III regulator MAFR-1 in regulating sperm quality in Caenorhabditis elegans. Hammerquist AM, et al. Sci Rep, 2020 Nov 9. PMID 33168938, Free PMC Article
  5. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in late endosome to vacuole transport via multivesicular body sorting pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in vacuolar transport IEA
Inferred from Electronic Annotation
more info
  
involved_in vesicle budding from membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of ESCRT III complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasmic side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in multivesicular body IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Charged multivesicular body protein 7
NP_495933.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    9054972..9056504
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063532.8 → NP_495933.1  Charged multivesicular body protein 7 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495933.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q22718
    Conserved Domains (1) summary
    pfam03357
    Location:217 → 384
    Snf7
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.