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kin-15 Protein kinase domain-containing protein;Receptor-like tyrosine-protein kinase kin-15 [ Caenorhabditis elegans ]

Gene ID: 174498, updated on 4-Jan-2025

Summary

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Official Symbol
kin-15
Official Full Name
Protein kinase domain-containing protein;Receptor-like tyrosine-protein kinase kin-15
Primary source
WormBase:WBGene00002199
Locus tag
CELE_M176.6
See related
AllianceGenome:WB:WBGene00002199
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in cell surface receptor protein tyrosine kinase signaling pathway. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in hyp6 and hyp7 syncytium. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See kin-15 in Genome Data Viewer
Location:
chromosome: II
Exon count:
9
Sequence:
Chromosome: II; NC_003280.10 (9431383..9433709, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Venom protein Neighboring gene ncRNA Neighboring gene Receptor-like tyrosine-protein kinase kin-16 Neighboring gene GH18 domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The protein kinases of Caenorhabditis elegans: a model for signal transduction in multicellular organisms. Plowman GD, et al. Proc Natl Acad Sci U S A, 1999 Nov 23. PMID 10570119, Free PMC Article
  2. Two novel transmembrane protein tyrosine kinases expressed during Caenorhabditis elegans hypodermal development. Morgan WR, et al. Mol Cell Biol, 1993 Nov. PMID 8413302, Free PMC Article
  3. The family of Caenorhabditis elegans tyrosine kinase receptors: similarities and differences with mammalian receptors. Popovici C, et al. Genome Res, 1999 Nov. PMID 10568743
  4. Paralogy and orthology of tyrosine kinases that can extend the life span of Caenorhabditis elegans. Rikke BA, et al. Mol Biol Evol, 2000 May. PMID 10779528
  5. Molecular genetics. Operons in eukaryotes follow the spliced leader. Hirsh D. Nature, 1994 Nov 17. PMID 7969465

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane receptor protein tyrosine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in multicellular organism development IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
part_of receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Protein kinase domain-containing protein;Receptor-like tyrosine-protein kinase kin-15
NP_741034.2
  • Confirmed by transcript evidence
NP_741035.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    9431383..9433709 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_171855.4 → NP_741035.2  Receptor-like tyrosine-protein kinase kin-15 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741035.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34891
    Conserved Domains (2) summary
    smart00221
    Location:147 → 452
    STYKc; Protein kinase; unclassified specificity
    cd00192
    Location:148 → 453
    PTKc; Catalytic domain of Protein Tyrosine Kinases

  2. NM_171029.8 → NP_741034.2  Protein kinase domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741034.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T8M7
    Conserved Domains (1) summary
    cd00192
    Location:88 → 393
    PTKc; Catalytic domain of Protein Tyrosine Kinases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P34891.1

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