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npp-19 Nucleoporin NUP35 [ Caenorhabditis elegans ]

Gene ID: 174663, updated on 9-Dec-2024

Summary

Official Symbol
npp-19
Official Full Name
Nucleoporin NUP35
Primary source
WormBase:WBGene00003805
Locus tag
CELE_R06F6.5
See related
AllianceGenome:WB:WBGene00003805
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable phospholipid binding activity. Predicted to be a structural constituent of nuclear pore. Involved in embryo development; nucleus organization; and regulation of exit from mitosis. Located in nuclear envelope. Part of nuclear pore. Is expressed in body wall musculature; nervous system; and pharynx. Orthologous to human NUP35 (nucleoporin 35). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See npp-19 in Genome Data Viewer
Location:
chromosome: II
Exon count:
7
Sequence:
Chromosome: II; NC_003280.10 (10796653..10798479, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Vacuolar protein sorting-associated protein 11 homolog Neighboring gene SET domain-containing protein 14 Neighboring gene ncRNA Neighboring gene Homeobox protein ceh-62

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables phospholipid binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of nuclear pore IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of nuclear pore IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in NLS-bearing protein import into nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cell cycle IEA
Inferred from Electronic Annotation
more info
 
involved_in cell division IEA
Inferred from Electronic Annotation
more info
 
involved_in embryo development ending in birth or egg hatching IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in mRNA transport IEA
Inferred from Electronic Annotation
more info
 
involved_in nuclear pore organization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in nucleocytoplasmic transport IEA
Inferred from Electronic Annotation
more info
 
involved_in nucleus organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of exit from mitosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear envelope IDA
Inferred from Direct Assay
more info
PubMed 
located_in nuclear membrane IEA
Inferred from Electronic Annotation
more info
 
part_of nuclear pore IDA
Inferred from Direct Assay
more info
PubMed 
part_of nuclear pore IEA
Inferred from Electronic Annotation
more info
 
part_of nuclear pore central transport channel IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of nuclear pore nuclear basket IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Nucleoporin NUP35
NP_496324.1
  • Confirmed by transcript evidence
NP_496325.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    10796653..10798479 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063923.7NP_496324.1  Nucleoporin NUP35 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496324.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O62340, Q09601
    Conserved Domains (1) summary
    pfam05172
    Location:195275
    Nup35_RRM; Nup53/35/40-type RNA recognition motif
  2. NM_063924.7NP_496325.1  Nucleoporin NUP35 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496325.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q09601
    Conserved Domains (1) summary
    pfam05172
    Location:195275
    Nup35_RRM; Nup53/35/40-type RNA recognition motif