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samp-1 Transmembrane protein 201 homolog [ Caenorhabditis elegans ]

Gene ID: 174727, updated on 9-Dec-2024

Summary

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Official Symbol
samp-1
Official Full Name
Transmembrane protein 201 homolog
Primary source
WormBase:WBGene00011994
Locus tag
CELE_T24F1.2
See related
AllianceGenome:WB:WBGene00011994
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable actin filament binding activity and lamin binding activity. Involved in embryo development and nuclear migration along microtubule. Located in nuclear envelope. Orthologous to human TMEM201 (transmembrane protein 201). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See samp-1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
7
Sequence:
Chromosome: II; NC_003280.10 (11302891..11305626)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Serine/threonine-protein phosphatase 6 regulatory subunit Neighboring gene GTP-binding protein Neighboring gene Ras association domain-containing protein 1 homolog Neighboring gene ncRNA Neighboring gene Small integral membrane protein 36 Neighboring gene EGF-like domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Caenorhabditis elegans SUN protein UNC-84 interacts with lamin to transfer forces from the cytoplasm to the nucleoskeleton during nuclear migration. Bone CR, et al. Mol Biol Cell, 2014 Sep 15. PMID 25057012, Free PMC Article
  2. Predictive models of molecular machines involved in Caenorhabditis elegans early embryogenesis. Gunsalus KC, et al. Nature, 2005 Aug 11. PMID 16094371
  3. A combined binary interaction and phenotypic map of C. elegans cell polarity proteins. Koorman T, et al. Nat Cell Biol, 2016 Mar. PMID 26780296, Free PMC Article
  4. In Vivo Interaction Proteomics in Caenorhabditis elegans Embryos Provides New Insights into P Granule Dynamics. Chen JX, et al. Mol Cell Proteomics, 2016 May. PMID 26912668, Free PMC Article
  5. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables lamin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in embryo development ending in birth or egg hatching IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in nuclear migration along microtubule IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in nuclear migration along microtubule IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in nuclear envelope IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nuclear inner membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in nuclear membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Transmembrane protein 201 homolog
NP_496416.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    11302891..11305626
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064015.7 → NP_496416.1  Transmembrane protein 201 homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496416.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q22747
    Conserved Domains (1) summary
    pfam09779
    Location:29 → 158
    Ima1_N; Ima1 N-terminal domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q22747.1

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