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Y17G7B.17 Myeloid leukemia factor [ Caenorhabditis elegans ]

Gene ID: 174849, updated on 4-Jan-2025

Summary

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Official Symbol
Y17G7B.17
Official Full Name
Myeloid leukemia factor
Primary source
WormBase:WBGene00012468
Locus tag
CELE_Y17G7B.17
See related
AllianceGenome:WB:WBGene00012468
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in regulation of DNA-templated transcription. Predicted to be active in cytoplasm and nucleus. Orthologous to several human genes including MLF2 (myeloid leukemia factor 2). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See Y17G7B.17 in Genome Data Viewer
Location:
chromosome: II
Exon count:
6
Sequence:
Chromosome: II; NC_003280.10 (12092419..12099989, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene C2H2-type domain-containing protein Neighboring gene ANK_REP_REGION domain-containing protein;Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2;Truncated ctn-1 Neighboring gene putative RNA methyltransferase Y17G7B.18 Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Myeloid leukemia factor
NP_496571.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    12092419..12099989 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064170.9 → NP_496571.2  Myeloid leukemia factor [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496571.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9XXH7
    Conserved Domains (1) summary
    pfam10248
    Location:53 → 193
    Mlf1IP; Myelodysplasia-myeloid leukemia factor 1-interacting protein
Nucleotide Protein
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