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ptr-18 Patched-related protein 18 [ Caenorhabditis elegans ]

Gene ID: 174940, updated on 4-Jan-2025

Summary

Official Symbol
ptr-18
Official Full Name
Patched-related protein 18
Primary source
WormBase:WBGene00004232
Locus tag
CELE_Y38F1A.3
See related
AllianceGenome:WB:WBGene00004232
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in endocytosis and molting cycle. Acts upstream of or within nematode male tail mating organ morphogenesis. Located in apical plasma membrane. Is expressed in hypodermal cell and ventral cord blast cell. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

See ptr-18 in Genome Data Viewer
Location:
chromosome: II
Exon count:
11
Sequence:
Chromosome: II; NC_003280.10 (12965546..12978171)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Exocyst complex component Sec10 Neighboring gene ncRNA Neighboring gene E3 ubiquitin-protein ligase RNF170 Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein Neighboring gene ncRNA Neighboring gene G1/S-specific cyclin-D Neighboring gene Hydroxyacid-oxoacid transhydrogenase, mitochondrial

General gene information

Markers

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in endocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in molting cycle, collagen and cuticulin-based cuticle IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in molting cycle, collagen and cuticulin-based cuticle IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within nematode male tail mating organ morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in apical plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytoplasmic vesicle membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Patched-related protein 18
NP_496761.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    12965546..12978171
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064360.5NP_496761.3  Patched-related protein 18 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496761.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9XWL9
    Conserved Domains (1) summary
    cl25655
    Location:72834
    Patched; Patched family