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taco-1 Transcriptional regulatory protein [ Caenorhabditis elegans ]

Gene ID: 175191, updated on 9-Dec-2024

Summary

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Official Symbol
taco-1
Official Full Name
Transcriptional regulatory protein
Primary source
WormBase:WBGene00021757
Locus tag
CELE_Y50D7A.9
See related
AllianceGenome:WB:WBGene00021757
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 8. Orthologous to human TACO1 (translational activator of cytochrome c oxidase I). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See taco-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
5
Sequence:
Chromosome: III; NC_003281.10 (284117..289438)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Protein kinase domain-containing protein;phosphorylase kinase Neighboring gene DNA 5'-3' helicase Neighboring gene ncRNA Neighboring gene 30S ribosomal protein S15;Peptidase metallopeptidase domain-containing protein Neighboring gene DUF295 domain-containing protein;F-box domain-containing protein Neighboring gene ncRNA Neighboring gene Alkyldihydroxyacetonephosphate synthase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Trifunctional cross-linker for mapping protein-protein interaction networks and comparing protein conformational states. Tan D, et al. Elife, 2016 Mar 8. PMID 26952210, Free PMC Article
  2. Gene regulatory network inference in long-lived C. elegans reveals modular properties that are predictive of novel aging genes. Suriyalaksh M, et al. iScience, 2022 Jan 21. PMID 35036864, Free PMC Article
  3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Transcriptional regulatory protein
NP_497183.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    284117..289438
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064782.5 → NP_497183.1  Transcriptional regulatory protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497183.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q965T4
    Conserved Domains (1) summary
    pfam01709
    Location:45 → 281
    Transcrip_reg; Transcriptional regulator
Nucleotide Protein
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