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tag-340 START domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 175655, updated on 4-Jan-2025

Summary

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Official Symbol
tag-340
Official Full Name
START domain-containing protein
Primary source
WormBase:WBGene00017826
Locus tag
CELE_F26F4.4
See related
AllianceGenome:WB:WBGene00017826
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable lipid binding activity. Predicted to be involved in vesicle tethering to endoplasmic reticulum. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum-endosome membrane contact site and late endosome membrane. Predicted to colocalize with endoplasmic reticulum membrane. Orthologous to several human genes including STARD3 (StAR related lipid transfer domain containing 3). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See tag-340 in Genome Data Viewer
Location:
chromosome: III
Exon count:
9
Sequence:
Chromosome: III; NC_003281.10 (4900508..4903170)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene RING-type E3 ubiquitin transferase Neighboring gene ncRNA Neighboring gene Mediator of RNA polymerase II transcription subunit 21 Neighboring gene C2H2-type domain-containing protein Neighboring gene Rhomboid-related protein 1 Neighboring gene ANK_REP_REGION domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables lipid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in vesicle tethering to endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
colocalizes_with endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endoplasmic reticulum-endosome membrane contact site IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in late endosome membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
START domain-containing protein
NP_001379724.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    4900508..4903170
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001393331.1 → NP_001379724.1  START domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q19819
    Conserved Domains (2) summary
    pfam01852
    Location:246 → 441
    START; START domain
    pfam10457
    Location:18 → 192
    MENTAL; Cholesterol-capturing domain
Nucleotide Protein
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