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nop-1 Pseudocleavage protein nop-1 [ Caenorhabditis elegans ]

Gene ID: 175845, updated on 9-Dec-2024

Summary

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Official Symbol
nop-1
Official Full Name
Pseudocleavage protein nop-1
Primary source
WormBase:WBGene00017774
Locus tag
CELE_F25B5.2
See related
AllianceGenome:WB:WBGene00017774
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in anterior/posterior axis specification, embryo and mitotic cytokinesis. Located in cell cortex; cleavage furrow; and nucleus. Is expressed in embryonic cell. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See nop-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
11
Sequence:
Chromosome: III; NC_003281.10 (5958722..5962325)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene 5'-nucleotidase;Putative cytosolic 5'-nucleotidase 3;Transposase Neighboring gene NOPS domain-containing protein;RRM domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Protein dct-6 Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pseudocleavage is dispensable for polarity and development in C. elegans embryos. Rose LS, et al. Dev Biol, 1995 Apr. PMID 7729583
  2. An interphase contractile ring reshapes primordial germ cells to allow bulk cytoplasmic remodeling. Maniscalco C, et al. J Cell Biol, 2020 Feb 3. PMID 31819975, Free PMC Article
  3. LET-99 functions in the astral furrowing pathway, where it is required for myosin enrichment in the contractile ring. Price KL, et al. Mol Biol Cell, 2017 Sep 1. PMID 28701343, Free PMC Article
  4. RhoA activation during polarization and cytokinesis of the early Caenorhabditis elegans embryo is differentially dependent on NOP-1 and CYK-4. Tse YC, et al. Mol Biol Cell, 2012 Oct. PMID 22918944, Free PMC Article
  5. A genome-wide RNAi screen for enhancers of par mutants reveals new contributors to early embryonic polarity in Caenorhabditis elegans. Morton DG, et al. Genetics, 2012 Nov. PMID 22887819, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. An interphase contractile ring reshapes primordial germ cells to allow bulk cytoplasmic remodeling.
    Title: An interphase contractile ring reshapes primordial germ cells to allow bulk cytoplasmic remodeling.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in anterior/posterior axis specification, embryo IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cell cycle IEA
Inferred from Electronic Annotation
more info
  
involved_in cell division IEA
Inferred from Electronic Annotation
more info
  
involved_in mitotic cytokinesis IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cell cortex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cell cortex IEA
Inferred from Electronic Annotation
more info
  
located_in cleavage furrow IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cleavage furrow IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Pseudocleavage protein nop-1
NP_001293631.1
  • Confirmed by transcript evidence
NP_498298.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    5958722..5962325
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001306702.2 → NP_001293631.1  Pseudocleavage protein nop-1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001293631.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    J7H8Z6, Q09314, W6RY41

  2. NM_065897.7 → NP_498298.1  Pseudocleavage protein nop-1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498298.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q09314
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q09314.2

Gene LinkOut

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