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mob-4 MOB-like protein phocein [ Caenorhabditis elegans ]

Gene ID: 176158, updated on 2-Nov-2024

Summary

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Official Symbol
mob-4
Official Full Name
MOB-like protein phocein
Primary source
WormBase:WBGene00016238
Locus tag
CELE_C30A5.3
See related
AllianceGenome:WB:WBGene00016238
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable metal ion binding activity. Predicted to be located in Golgi cisterna membrane and perinuclear region of cytoplasm. Predicted to be active in cytoplasm. Is expressed widely. Orthologous to human MOB4 (MOB family member 4, phocein). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See mob-4 in Genome Data Viewer
Location:
chromosome: III
Exon count:
5
Sequence:
Chromosome: III; NC_003281.10 (8225097..8226380)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene pseudo Neighboring gene RAD51-like protein 1 Neighboring gene ncRNA Neighboring gene F-box/LRR-repeat protein fbxl-1 Neighboring gene Small RNA 2'-O-methyltransferase Neighboring gene MBL fold metallo-hydrolase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Loss of Caenorhabditis elegans homologue of human MOB4 compromises life span, health life span and thermotolerance. Jahan M, et al. Genes Cells, 2021 Oct. PMID 34428327
  2. STRIPAK regulation of katanin microtubule severing in the Caenorhabditis elegans embryo. Lu T, et al. Genetics, 2022 May 5. PMID 35298637, Free PMC Article
  3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi cisterna membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
MOB-like protein phocein
NP_498798.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    8225097..8226380
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_066397.6 → NP_498798.2  MOB-like protein phocein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498798.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34349
    Conserved Domains (1) summary
    pfam03637
    Location:44 → 208
    Mob1_phocein; Mob1/phocein family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P34349.2

Gene LinkOut

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