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lmbr-1 LIMR family protein R05D3.2 [ Caenorhabditis elegans ]

Gene ID: 176182, updated on 9-Dec-2024

Summary

Official Symbol
lmbr-1
Official Full Name
LIMR family protein R05D3.2
Primary source
WormBase:WBGene00019877
Locus tag
CELE_R05D3.2
See related
AllianceGenome:WB:WBGene00019877
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in signal transduction. Predicted to be active in plasma membrane. Is expressed in several structures, including enteric muscle; hypodermis; intestine; nervous system; and vulval muscle. Used to study bone development disease. Human ortholog(s) of this gene implicated in Laurin-Sandrow syndrome; acheiropody; and syndactyly type 4. Orthologous to human LMBR1 (limb development membrane protein 1) and LMBR1L (limb development membrane protein 1 like). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See lmbr-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
7
Sequence:
Chromosome: III; NC_003281.10 (8372270..8375220)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Putative zinc finger protein R05D3.3 Neighboring gene ncRNA Neighboring gene Histone-lysine N-methyltransferase met-2 Neighboring gene DNA topoisomerase 2;Putative DNA topoisomerase 2, mitochondrial

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables transmembrane signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
LIMR family protein R05D3.2
NP_001411903.1
  • Confirmed by transcript evidence
NP_498847.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    8372270..8375220
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_066446.7NP_498847.1  LIMR family protein R05D3.2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498847.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34535
    Conserved Domains (1) summary
    pfam04791
    Location:74693
    LMBR1; LMBR1-like membrane protein
  2. NM_001424973.1NP_001411903.1  LIMR family protein R05D3.2 [Caenorhabditis elegans]

    Status: REVIEWED