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tba-7 Tubulin alpha chain [ Caenorhabditis elegans ]

Gene ID: 176568, updated on 2-Nov-2024

Summary

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Official Symbol
tba-7
Official Full Name
Tubulin alpha chain
Primary source
WormBase:WBGene00006533
Locus tag
CELE_T28D6.2
See related
AllianceGenome:WB:WBGene00006533
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to be active in cytoplasm and microtubule. Is expressed in touch receptor neurons. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See tba-7 in Genome Data Viewer
Location:
chromosome: III
Exon count:
5
Sequence:
Chromosome: III; NC_003281.10 (11368351..11371788, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ANK_REP_REGION domain-containing protein Neighboring gene ncRNA Neighboring gene Cystatin domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Prolyl 4-hydroxylase subunit alpha-1 Neighboring gene Glycosyltransferase family 92 protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Correction for Distinct effects of tubulin isotype mutations on neurite growth in Caenorhabditis elegans. . Mol Biol Cell, 2017 Dec 1. PMID 29187573, Free PMC Article
  2. Distinct effects of tubulin isotype mutations on neurite growth in Caenorhabditis elegans. Zheng C, et al. Mol Biol Cell, 2017 Oct 15. PMID 28835377, Free PMC Article
  3. A novel, essential trans-splicing protein connects the nematode SL1 snRNP to the CBC-ARS2 complex. Fasimoye RY, et al. Nucleic Acids Res, 2022 Jul 22. PMID 35736244, Free PMC Article
  4. Microtubule plus-end dynamics link wound repair to the innate immune response. Taffoni C, et al. Elife, 2020 Jan 29. PMID 31995031, Free PMC Article
  5. Yolk-deprived Caenorhabditis elegans secure brood size at the expense of competitive fitness. Geens E, et al. Life Sci Alliance, 2023 Jun. PMID 37059473, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in microtubule-based process IEA
Inferred from Electronic Annotation
more info
  
involved_in mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in microtubule IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Tubulin alpha chain
NP_499463.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    11368351..11371788 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_067062.7 → NP_499463.1  Tubulin alpha chain [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_499463.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O18154
    Conserved Domains (2) summary
    PTZ00335
    Location:1 → 443
    PTZ00335; tubulin alpha chain; Provisional
    cd02186
    Location:2 → 430
    alpha_tubulin; The alpha-tubulin family
Nucleotide Protein
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