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nlp-21 Neuropeptide-Like Protein [ Caenorhabditis elegans ]

Gene ID: 176570, updated on 4-Jan-2025

Summary

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Official Symbol
nlp-21
Official Full Name
Neuropeptide-Like Protein
Primary source
WormBase:WBGene00003759
Locus tag
CELE_Y47D3B.2
See related
AllianceGenome:WB:WBGene00003759
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in neuropeptide signaling pathway. Is expressed in body wall musculature; dorsal nerve cord; intestine; and neurons. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See nlp-21 in Genome Data Viewer
Location:
chromosome: III
Exon count:
3
Sequence:
Chromosome: III; NC_003281.10 (11388624..11393262, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Prolyl 4-hydroxylase subunit alpha-1 Neighboring gene Glycosyltransferase family 92 protein Neighboring gene ncRNA Neighboring gene Abnormal cell migration protein 18-like fibronectin type I domain-containing protein Neighboring gene IGFBP N-terminal domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Co-expression of the transcription factors CEH-14 and TTX-1 regulates AFD neuron-specific genes gcy-8 and gcy-18 in C. elegans. Kagoshima H, et al. Dev Biol, 2015 Mar 15. PMID 25614239
  2. The scaffolding protein SYD-2/Liprin-α regulates the mobility and polarized distribution of dense-core vesicles in C. elegans motor neurons. Goodwin PR, et al. PLoS One, 2013. PMID 23358451, Free PMC Article
  3. PKC-1 regulates secretion of neuropeptides. Sieburth D, et al. Nat Neurosci, 2007 Jan. PMID 17128266
  4. Two Rab2 interactors regulate dense-core vesicle maturation. Ailion M, et al. Neuron, 2014 Apr 2. PMID 24698274, Free PMC Article
  5. Peptidomics of Caenorhabditis elegans: in search of neuropeptides. Husson SJ, et al. Commun Agric Appl Biol Sci, 2005. PMID 16366296

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in neuropeptide signaling pathway IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Neuropeptide-Like Protein
NP_001359616.1
  • Product from WormBase gene class nlp;
    Confirmed by transcript evidence
NP_499466.1
  • Product from WormBase gene class nlp;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    11388624..11393262 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001372660.2 → NP_001359616.1  Neuropeptide-Like Protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9U2B9

  2. NM_067065.6 → NP_499466.1  Neuropeptide-Like Protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_499466.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9XX02
Nucleotide Protein
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