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pph-4.2 Serine/threonine-protein phosphatase 4 catalytic subunit 2 [ Caenorhabditis elegans ]

Gene ID: 176663, updated on 2-Nov-2024

Summary

Official Symbol
pph-4.2
Official Full Name
Serine/threonine-protein phosphatase 4 catalytic subunit 2
Primary source
WormBase:WBGene00004086
Locus tag
CELE_Y49E10.3
See related
AllianceGenome:WB:WBGene00004086
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in double-strand break repair via homologous recombination. Predicted to be active in cytoplasm and nucleus. Orthologous to human PPP4C (protein phosphatase 4 catalytic subunit). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See pph-4.2 in Genome Data Viewer
Location:
chromosome: III
Exon count:
4
Sequence:
Chromosome: III; NC_003281.10 (12374173..12377248, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Histone H3.3 type 2 Neighboring gene ncRNA Neighboring gene 26S proteasome regulatory subunit 8 Neighboring gene Glutaredoxin domain-containing protein Neighboring gene pseudo Neighboring gene Thioredoxin domain-containing protein

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables myosin phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables phosphoprotein phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein serine/threonine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in double-strand break repair via homologous recombination IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Serine/threonine-protein phosphatase 4 catalytic subunit 2
NP_001022898.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    12374173..12377248 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001027727.6NP_001022898.1  Serine/threonine-protein phosphatase 4 catalytic subunit 2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022898.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q966Q3, Q9XTT8
    Conserved Domains (2) summary
    PTZ00239
    Location:16321
    PTZ00239; serine/threonine protein phosphatase 2A; Provisional
    cd07415
    Location:16303
    MPP_PP2A_PP4_PP6; PP2A, PP4, and PP6 phosphoprotein phosphatases, metallophosphatase domain