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garr-1 putative H/ACA ribonucleoprotein complex subunit 1-like protein [ Caenorhabditis elegans ]

Gene ID: 176870, updated on 9-Dec-2024

Summary

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Official Symbol
garr-1
Official Full Name
putative H/ACA ribonucleoprotein complex subunit 1-like protein
Primary source
WormBase:WBGene00022046
Locus tag
CELE_Y66H1A.4
See related
AllianceGenome:WB:WBGene00022046
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable box H/ACA snoRNA binding activity. Predicted to be involved in snoRNA guided rRNA pseudouridine synthesis. Predicted to be located in nucleolus. Predicted to be part of box H/ACA snoRNP complex. Orthologous to human GAR1 (GAR1 ribonucleoprotein). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See garr-1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
2
Sequence:
Chromosome: IV; NC_003282.8 (426168..427204)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene 3'-5' exonuclease eri-1 Neighboring gene Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase daf-18 Neighboring gene Saposin B-type domain-containing protein Neighboring gene ncRNA Neighboring gene Myosin motor domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Subsequent infection differentially affects the proteome of Caenorhabditis elegans by abrogating the intestinal cell proliferation. Udayakumar P, et al. Microb Pathog, 2022 Jan. PMID 34952153
  2. Microarray analysis of ncRNA expression patterns in Caenorhabditis elegans after RNAi against snoRNA associated proteins. Aftab MN, et al. BMC Genomics, 2008 Jun 11. PMID 18547420, Free PMC Article
  3. RG/RGG repeats in the C. elegans homologs of Nucleolin and GAR1 contribute to sub-nucleolar phase separation. Spaulding EL, et al. Nat Commun, 2022 Nov 3. PMID 36329008, Free PMC Article
  4. Box C/D small nucleolar ribonucleoproteins regulate mitochondrial surveillance and innate immunity. Tjahjono E, et al. PLoS Genet, 2022 Mar. PMID 35275914, Free PMC Article
  5. Identification of conserved pathways of DNA-damage response and radiation protection by genome-wide RNAi. van Haaften G, et al. Curr Biol, 2006 Jul 11. PMID 16824923

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables box H/ACA snoRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in pseudouridine synthesis IEA
Inferred from Electronic Annotation
more info
  
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in snoRNA guided rRNA pseudouridine synthesis IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of box H/ACA snoRNP complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
putative H/ACA ribonucleoprotein complex subunit 1-like protein
NP_499927.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    426168..427204
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_067526.4 → NP_499927.2  putative H/ACA ribonucleoprotein complex subunit 1-like protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_499927.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9TYK1
    Conserved Domains (1) summary
    pfam04410
    Location:52 → 148
    Gar1; Gar1/Naf1 RNA binding region
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9TYK1.2

Gene LinkOut

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