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hrpu-2 RRM domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 177011, updated on 2-Nov-2024

Summary

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Official Symbol
hrpu-2
Official Full Name
RRM domain-containing protein
Primary source
WormBase:WBGene00022134
Locus tag
CELE_Y71G10AL.1
See related
AllianceGenome:WB:WBGene00022134
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Is expressed in body wall musculature; intestinal cell; motor neurons; pharyngeal muscle cell; and somatic neurons. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See hrpu-2 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
13
Sequence:
Chromosome: IV; NC_003282.8 (2177896..2198937)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene P3 protein Neighboring gene Eukaryotic translation initiation factor 3 30 kDa subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. HRPU-2, a Homolog of Mammalian hnRNP U, Regulates Synaptic Transmission by Controlling the Expression of SLO-2 Potassium Channel in Caenorhabditis elegans. Liu P, et al. J Neurosci, 2018 Jan 31. PMID 29217678, Free PMC Article
  2. The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription. Akay A, et al. Dev Cell, 2017 Aug 7. PMID 28787591, Free PMC Article
  3. Functional identification of microRNA-centered complexes in C. elegans. Hebbar S, et al. Sci Rep, 2022 May 3. PMID 35504914, Free PMC Article
  4. Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences. Zhang X, et al. PLoS Genet, 2021 Jun. PMID 34166401, Free PMC Article
  5. SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans. Robert VJ, et al. Development, 2023 Nov 1. PMID 37818613, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. mutations of HRPU-2, a worm homolog of mammalian hnRNP U, result in dysfunction of a Slo2 potassium channel, which is critical to neuronal function
    Title: HRPU-2, a Homolog of Mammalian hnRNP U, Regulates Synaptic Transmission by Controlling the Expression of SLO-2 Potassium Channel in Caenorhabditis elegans.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

General protein information

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Preferred Names
RRM domain-containing protein
NP_741334.3
  • Confirmed by transcript evidence
NP_741335.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    2177896..2198937
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_171899.6 → NP_741335.2  RRM domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741335.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    G4SPY1, Q8MXS3

  2. NM_171284.5 → NP_741334.3  RRM domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741334.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    G4SPY0, Q3V5J6
Nucleotide Protein
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