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ugt-45 glucuronosyltransferase [ Caenorhabditis elegans ]

Gene ID: 177139, updated on 4-Jan-2025

Summary

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Official Symbol
ugt-45
Official Full Name
glucuronosyltransferase
Primary source
WormBase:WBGene00021372
Locus tag
CELE_Y37E11AR.5
See related
AllianceGenome:WB:WBGene00021372
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Orthologous to human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See ugt-45 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
6
Sequence:
Chromosome: IV; NC_003282.8 (3748210..3751101, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene E3 ubiquitin-protein ligase siah-1 Neighboring gene ncRNA Neighboring gene Ig-like domain-containing protein Neighboring gene Bestrophin homolog

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Aryl Hydrocarbon Receptor-Dependent and -Independent Pathways Mediate Curcumin Anti-Aging Effects. Brinkmann V, et al. Antioxidants (Basel), 2022 Mar 23. PMID 35453298, Free PMC Article
  2. Differential expression of genes in C. elegans reveals transcriptional responses to indirect-acting xenobiotic compounds and insensitivity to 2,3,7,8-tetrachlorodibenzodioxin. Karengera A, et al. Ecotoxicol Environ Saf, 2022 Mar 15. PMID 35219257
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables UDP-glycosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables UDP-glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glucuronosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
glucuronosyltransferase
NP_001294295.1
  • Confirmed by transcript evidence
NP_500410.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    3748210..3751101 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_068009.7 → NP_500410.2  glucuronosyltransferase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_500410.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q965X5
    Conserved Domains (2) summary
    PHA03392
    Location:14 → 513
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:19 → 510
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

  2. NM_001307366.3 → NP_001294295.1  glucuronosyltransferase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294295.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PLL6
    Conserved Domains (2) summary
    PHA03392
    Location:11 → 482
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:9 → 479
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase
Nucleotide Protein
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