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cal-3 EF-hand domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 177143, updated on 9-Dec-2024

Summary

Official Symbol
cal-3
Official Full Name
EF-hand domain-containing protein
Primary source
WormBase:WBGene00000287
Locus tag
CELE_M02B7.6
See related
AllianceGenome:WB:WBGene00000287
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable calcium ion binding activity. Predicted to be active in centrosome and cytoplasm. Orthologous to human CALML3 (calmodulin like 3); CALML4 (calmodulin like 4); and CALML5 (calmodulin like 5). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See cal-3 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
7
Sequence:
Chromosome: IV; NC_003282.8 (3829493..3835165, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene FTH domain-containing protein Neighboring gene DUF1014-domain-containing protein Neighboring gene SEC7 domain-containing protein Neighboring gene Neuropeptide-Like Protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
EF-hand domain-containing protein
NP_001294291.1
  • Confirmed by transcript evidence
NP_500421.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    3829493..3835165 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_068020.7NP_500421.2  EF-hand domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_500421.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    G4SFU6, Q94288
    Conserved Domains (2) summary
    PTZ00184
    Location:92232
    PTZ00184; calmodulin; Provisional
    cd00051
    Location:100162
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
  2. NM_001307362.3NP_001294291.1  EF-hand domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294291.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PQW9
    Conserved Domains (2) summary
    PTZ00184
    Location:22162
    PTZ00184; calmodulin; Provisional
    cd00051
    Location:3092
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...