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kin-36 Protein kinase domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 177234, updated on 4-Jan-2025

Summary

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Official Symbol
kin-36
Official Full Name
Protein kinase domain-containing protein
Primary source
WormBase:WBGene00020678
Locus tag
CELE_T22B11.4
See related
AllianceGenome:WB:WBGene00020678
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in cell surface receptor protein tyrosine kinase signaling pathway. Predicted to be located in membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in pharynx and vulval cell. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See kin-36 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
12
Sequence:
Chromosome: IV; NC_003282.8 (4679018..4685732)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene N-acetylgalactosaminide beta-1,3-galactosyltransferase Neighboring gene AMOP domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. trim-21 promotes proteasomal degradation of CED-1 for apoptotic cell clearance in C. elegans. Yuan L, et al. Elife, 2022 Aug 5. PMID 35929733, Free PMC Article
  2. FGF negatively regulates muscle membrane extension in Caenorhabditis elegans. Dixon SJ, et al. Development, 2006 Apr. PMID 16495308
  3. Genomic overview of protein kinases. Manning G. WormBook, 2005 Dec 13. PMID 18050405, Free PMC Article
  4. Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly. Schaan Profes M, et al. PLoS Biol, 2024 Jan. PMID 38252619, Free PMC Article
  5. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane receptor protein tyrosine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in multicellular organism development IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Protein kinase domain-containing protein
NP_001023393.1
  • Confirmed by transcript evidence
NP_001023394.1
  • Confirmed by transcript evidence
NP_001334224.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    4679018..4685732
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001028222.5 → NP_001023393.1  Protein kinase domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023393.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O44561

  2. NM_001347302.3 → NP_001334224.1  Protein kinase domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I6CMA1
    Conserved Domains (1) summary
    cl21453
    Location:592 → 860
    PKc_like; Protein Kinases, catalytic domain

  3. NM_001028223.5 → NP_001023394.1  Protein kinase domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023394.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2KZW6
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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