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cec-5 Chromo domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 177537, updated on 9-Dec-2024

Summary

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Official Symbol
cec-5
Official Full Name
Chromo domain-containing protein
Primary source
WormBase:WBGene00017993
Locus tag
CELE_F32E10.6
See related
AllianceGenome:WB:WBGene00017993
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable methylated histone binding activity. Predicted to be involved in chromosome attachment to the nuclear envelope and regulation of gene expression. Predicted to be active in nuclear inner membrane. Is expressed in head; midbody; and tail. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See cec-5 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
5
Sequence:
Chromosome: IV; NC_003282.8 (7578506..7580112, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Tudor domain-containing protein Neighboring gene Chromo domain-containing protein cec-4 Neighboring gene NUC153 domain-containing protein Neighboring gene Protein clarinet Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Systematic characterization of chromodomain proteins reveals an H3K9me1/2 reader regulating aging in C. elegans. Hou X, et al. Nat Commun, 2023 Mar 6. PMID 36878913, Free PMC Article
  2. A small RNA system ensures accurate homologous pairing and unpaired silencing of meiotic chromosomes. Tabara H, et al. EMBO J, 2023 Jun 1. PMID 37078421, Free PMC Article
  3. Gamma radiation induces life stage-dependent reprotoxicity in Caenorhabditis elegans via impairment of spermatogenesis. Maremonti E, et al. Sci Total Environ, 2019 Dec 10. PMID 31425988
  4. A transcriptional cofactor regulatory network for the C. elegans intestine. Horowitz BB, et al. G3 (Bethesda), 2023 Jul 5. PMID 37119809, Free PMC Article
  5. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables methylated histone binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables methylated histone binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in chromosome attachment to the nuclear envelope IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in chromosome attachment to the nuclear envelope IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of gene expression IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nuclear inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Chromo domain-containing protein
NP_001370694.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    7578506..7580112 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001383124.2 → NP_001370694.1  Chromo domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q19973
    Conserved Domains (1) summary
    cl28914
    Location:115 → 167
    CD_CSD; CHROMO (CHRromatin Organization Modifier) domains and chromo shadow domains
Nucleotide Protein
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