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sucg-1 Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial [ Caenorhabditis elegans ]

Gene ID: 177555, updated on 4-Jan-2025

Summary

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Official Symbol
sucg-1
Official Full Name
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial
Primary source
WormBase:WBGene00016844
Locus tag
CELE_C50F7.4
See related
AllianceGenome:WB:WBGene00016844
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable succinate-CoA ligase (GDP-forming) activity. Predicted to be involved in succinyl-CoA metabolic process and tricarboxylic acid cycle. Predicted to be located in cytoplasm. Predicted to be part of succinate-CoA ligase complex. Predicted to be active in mitochondrion. Is expressed in body wall musculature; intestine; non-striated muscle; and reproductive system. Orthologous to human SUCLG2 (succinate-CoA ligase GDP-forming subunit beta). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See sucg-1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
6
Sequence:
Chromosome: IV; NC_003282.8 (7728913..7730650)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene PEHE domain-containing protein;TPX2 domain-containing protein Neighboring gene Basic proline-rich protein Neighboring gene Poly-N-acetyllactosamine extension enzyme Neighboring gene PDZ domain-containing protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mitochondrial aconitase suppresses immunity by modulating oxaloacetate and the mitochondrial unfolded protein response. Kim E, et al. Nat Commun, 2023 Jun 22. PMID 37349299, Free PMC Article
  2. The RNA-binding protein repertoire of Arabidopsis thaliana. Marondedze C, et al. Sci Rep, 2016 Jul 11. PMID 27405932, Free PMC Article
  3. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
  4. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
  5. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables ligase activity IEA
Inferred from Electronic Annotation
more info
  
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
NOT enables succinate-CoA ligase (ADP-forming) activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables succinate-CoA ligase (GDP-forming) activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables succinate-CoA ligase (GDP-forming) activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in succinyl-CoA metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in tricarboxylic acid cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
part_of succinate-CoA ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial
NP_501266.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    7728913..7730650
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_068865.6 → NP_501266.1  Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_501266.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P53589
    Conserved Domains (3) summary
    PRK00696
    Location:21 → 410
    sucC; succinyl-CoA synthetase subunit beta; Provisional
    pfam00549
    Location:290 → 410
    Ligase_CoA; CoA-ligase
    pfam08442
    Location:21 → 231
    ATP-grasp_2; ATP-grasp domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53589.1

Gene LinkOut

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