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ndub-11 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial [ Caenorhabditis elegans ]

Gene ID: 177606, updated on 4-Jan-2025

Summary

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Official Symbol
ndub-11
Official Full Name
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial
Primary source
WormBase:WBGene00018361
Locus tag
CELE_F42G8.10
See related
AllianceGenome:WB:WBGene00018361
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be located in membrane and mitochondrion. Predicted to be part of respiratory chain complex I. Human ortholog(s) of this gene implicated in linear skin defects with multiple congenital anomalies 3 and nuclear type mitochondrial complex I deficiency 30. Orthologous to human NDUFB11 (NADH:ubiquinone oxidoreductase subunit B11). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See ndub-11 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
5
Sequence:
Chromosome: IV; NC_003282.8 (8128940..8130231, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Thioredoxin domain-containing protein Neighboring gene Rhodanese domain-containing protein Neighboring gene ncRNA Neighboring gene Molybdopterin-synthase sulfurtransferase Neighboring gene MARVEL domain-containing protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. AdipoR2 recruits protein interactors to promote fatty acid elongation and membrane fluidity. Ruiz M, et al. J Biol Chem, 2023 Jun. PMID 37164154, Free PMC Article
  2. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
  3. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
  4. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
  5. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
part_of respiratory chain complex I IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial
NP_001023201.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    8128940..8130231 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001028030.6 → NP_001023201.1  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023201.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O44509
    Conserved Domains (1) summary
    cl15848
    Location:93 → 150
    ESSS; ESSS subunit of NADH:ubiquinone oxidoreductase (complex I)
Nucleotide Protein
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