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slc-25A26 Mitochondrial carrier protein PET8 [ Caenorhabditis elegans ]

Gene ID: 177711, updated on 4-Jan-2025

Summary

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Official Symbol
slc-25A26
Official Full Name
Mitochondrial carrier protein PET8
Primary source
WormBase:WBGene00008364
Locus tag
CELE_D1046.3
See related
AllianceGenome:WB:WBGene00008364
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables S-adenosyl-L-methionine transmembrane transporter activity. Involved in mitochondrial S-adenosyl-L-methionine transmembrane transport. Located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 28. Orthologous to human SLC25A26 (solute carrier family 25 member 26). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See slc-25A26 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
4
Sequence:
Chromosome: IV; NC_003282.8 (8930442..8932791)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Cleavage and polyadenylation specificity factor subunit 6;RRM domain-containing protein Neighboring gene tRNA Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene MFS domain-containing protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mitochondrial S-adenosylmethionine deficiency induces mitochondrial unfolded protein response and extends lifespan in Caenorhabditis elegans. Chen TY, et al. Aging Cell, 2024 Apr. PMID 38361361, Free PMC Article
  2. RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. LeGendre JB, et al. J Biol Chem, 2013 Jan 25. PMID 23195953, Free PMC Article
  3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables S-adenosyl-L-methionine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables S-adenosyl-L-methionine transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial S-adenosyl-L-methionine transmembrane transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Mitochondrial carrier protein PET8
NP_501552.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    8930442..8932791
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069151.6 → NP_501552.1  Mitochondrial carrier protein PET8 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_501552.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q18934
    Conserved Domains (2) summary
    PTZ00168
    Location:12 → 257
    PTZ00168; mitochondrial carrier protein; Provisional
    pfam00153
    Location:180 → 264
    Mito_carr; Mitochondrial carrier protein
Nucleotide Protein
Heading Accession and Version

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