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tbc-3 Rab-GAP TBC domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 177845, updated on 9-Dec-2024

Summary

Official Symbol
tbc-3
Official Full Name
Rab-GAP TBC domain-containing protein
Primary source
WormBase:WBGene00009322
Locus tag
CELE_F32B6.8
See related
AllianceGenome:WB:WBGene00009322
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable GTPase activator activity. Located in Golgi apparatus. Is expressed in hermaphrodite distal tip cell; neurons; pharynx; rect_D; and seam cell. Orthologous to human TBC1D22A (TBC1 domain family member 22A) and TBC1D22B (TBC1 domain family member 22B). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See tbc-3 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
13
Sequence:
Chromosome: IV; NC_003282.8 (9899012..9902513)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Bestrophin homolog 13 Neighboring gene ncRNA

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables GTPase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
Rab-GAP TBC domain-containing protein
NP_001023164.1
  • Confirmed by transcript evidence
NP_001023165.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    9899012..9902513
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001027993.4NP_001023164.1  Rab-GAP TBC domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023164.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7JL36
    Conserved Domains (1) summary
    smart00164
    Location:170421
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
  2. NM_001027994.4NP_001023165.1  Rab-GAP TBC domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023165.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O45434
    Conserved Domains (1) summary
    smart00164
    Location:190441
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs