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F01G10.10 BPI2 domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 177907, updated on 4-Jan-2025

Summary

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Official Symbol
F01G10.10
Official Full Name
BPI2 domain-containing protein
Primary source
WormBase:WBGene00008512
Locus tag
CELE_F01G10.10
See related
AllianceGenome:WB:WBGene00008512
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable lipid binding activity. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in Crohn's disease. Orthologous to several human genes including LBP (lipopolysaccharide binding protein). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See F01G10.10 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
13
Sequence:
Chromosome: IV; NC_003282.8 (10246160..10249785)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Lipase Neighboring gene transketolase Neighboring gene Smad-related protein daf-14 Neighboring gene Ground-like domain-containing protein Neighboring gene Nematode Specific Peptide family, group D

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables lipid binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
BPI2 domain-containing protein
NP_501879.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    10246160..10249785
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069478.6 → NP_501879.3  BPI2 domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_501879.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    O17768
    Conserved Domains (2) summary
    smart00328
    Location:42 → 273
    BPI1; BPI/LBP/CETP N-terminal domain
    pfam02886
    Location:298 → 541
    LBP_BPI_CETP_C; LBP / BPI / CETP family, C-terminal domain
Nucleotide Protein
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