T25B9.1 Aminotransferase class I/classII large domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: T25B9.1
Official Full Name: Aminotransferase class I/classII large domain-containing protein
Primary source: WormBase:WBGene00012007
Locus tag: CELE_T25B9.1
See related: AllianceGenome:WB:WBGene00012007
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable glycine C-acetyltransferase activity; pyridoxal phosphate binding activity; and transaminase activity. Predicted to be involved in biosynthetic process and threonine catabolic process. Predicted to be active in mitochondrion. Orthologous to human GCAT (glycine C-acetyltransferase). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See T25B9.1 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 5

Sequence:: Chromosome: IV; NC_003282.8 (10748378..10750141, complement)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

T25B9.2 (e-PCR)
- UniSTS:306545

T25B9.1 (e-PCR)
- UniSTS:315095

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables glycine C-acetyltransferase activity	IEA Inferred from Electronic Annotation more info
enables pyridoxal phosphate binding	IEA Inferred from Electronic Annotation more info
enables transaminase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in threonine catabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Aminotransferase class I/classII large domain-containing protein

NP_501991.3

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

10748378..10750141 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_069590.8 → NP_501991.3 Aminotransferase class I/classII large domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

Q22768

Conserved Domains (1) summary

PRK06939
Location:12 → 403

PRK06939; 2-amino-3-ketobutyrate coenzyme A ligase; Provisional