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best-15 Bestrophin homolog 15 [ Caenorhabditis elegans ]

Gene ID: 177975, updated on 2-Nov-2024

Summary

Official Symbol
best-15
Official Full Name
Bestrophin homolog 15
Primary source
WormBase:WBGene00011258
Locus tag
CELE_R13.3
See related
AllianceGenome:WB:WBGene00011258
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Orthologous to human BEST2 (bestrophin 2) and BEST4 (bestrophin 4). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See best-15 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
12
Sequence:
Chromosome: IV; NC_003282.8 (10829549..10832248, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Paired domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene DBH-like monooxygenase protein 1;SET domain-containing protein Neighboring gene ncRNA

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables chloride channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables chloride channel activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in chloride transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in chloride transport IEA
Inferred from Electronic Annotation
more info
 
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of chloride channel complex IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Bestrophin homolog 15
NP_502007.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    10829549..10832248 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069606.9NP_502007.2  Bestrophin homolog 15 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_502007.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q21973
    Conserved Domains (1) summary
    pfam01062
    Location:8321
    Bestrophin; Bestrophin, RFP-TM, chloride channel