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dmd-6 DM domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 178392, updated on 9-Dec-2024

Summary

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Official Symbol
dmd-6
Official Full Name
DM domain-containing protein
Primary source
WormBase:WBGene00007058
Locus tag
CELE_F13G11.1
See related
AllianceGenome:WB:WBGene00007058
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II and sex differentiation. Predicted to be active in nucleus. Is expressed in several structures, including intestine; neurons; pharynx; rectum; and reproductive system. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See dmd-6 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
6
Sequence:
Chromosome: IV; NC_003282.8 (14616603..14623961)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
  2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sex differentiation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DM domain-containing protein
NP_001255816.1
  • Confirmed by transcript evidence
NP_001255817.1
  • Partially confirmed by transcript evidence
NP_001370045.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    14616603..14623961
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001383245.2 → NP_001370045.1  DM domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    O62159
    Conserved Domains (1) summary
    smart00301
    Location:41 → 94
    DM; Doublesex DNA-binding motif

  2. NM_001268887.3 → NP_001255816.1  DM domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255816.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D3YT85
    Conserved Domains (1) summary
    pfam03154
    Location:113 → 333
    Atrophin-1; Atrophin-1 family

  3. NM_001268888.3 → NP_001255817.1  DM domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255817.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D3YT86
    Conserved Domains (1) summary
    pfam03154
    Location:94 → 314
    Atrophin-1; Atrophin-1 family
Nucleotide Protein
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