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vti-1 t-SNARE coiled-coil homology domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 178397, updated on 2-Nov-2024

Summary

Official Symbol
vti-1
Official Full Name
t-SNARE coiled-coil homology domain-containing protein
Primary source
WormBase:WBGene00013302
Locus tag
CELE_Y57G11C.4
See related
AllianceGenome:WB:WBGene00013302
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable SNAP receptor activity and SNARE binding activity. Predicted to be involved in Golgi vesicle transport; macroautophagy; and retrograde transport, endosome to Golgi. Predicted to be located in several cellular components, including cytosol; endomembrane system; and intracellular membrane-bounded organelle. Predicted to be part of SNARE complex. Predicted to be active in Golgi apparatus; cytoplasmic vesicle membrane; and endoplasmic reticulum membrane. Orthologous to human VTI1A (vesicle transport through interaction with t-SNAREs 1A). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See vti-1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
3
Sequence:
Chromosome: IV; NC_003282.8 (14765632..14766665, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene SERPIN domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Small ribosomal subunit protein uS7m Neighboring gene Putative 6-phosphogluconolactonase

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables SNAP receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables SNAP receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables SNARE binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in Golgi to vacuole transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cellular component organization IEA
Inferred from Electronic Annotation
more info
 
involved_in intra-Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in macroautophagy IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in retrograde transport, endosome to Golgi IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in vesicle fusion with Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in ER to Golgi transport vesicle membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
part_of SNARE complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in endomembrane system IEA
Inferred from Electronic Annotation
more info
 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 
is_active_in late endosome membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
t-SNARE coiled-coil homology domain-containing protein
NP_502781.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    14765632..14766665 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_070380.5NP_502781.1  t-SNARE coiled-coil homology domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_502781.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O18230
    Conserved Domains (2) summary
    cd15891
    Location:132193
    SNARE_Vti1a; SNARE motif of Vti1b-like
    pfam05008
    Location:1898
    V-SNARE; Vesicle transport v-SNARE protein N-terminus