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ntl-11 CCR4-NOT transcription complex subunit 11;Secreted protein [ Caenorhabditis elegans ]

Gene ID: 178432, updated on 2-Nov-2024

Summary

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Official Symbol
ntl-11
Official Full Name
CCR4-NOT transcription complex subunit 11;Secreted protein
Primary source
WormBase:WBGene00013530
Locus tag
CELE_Y73F8A.25
See related
AllianceGenome:WB:WBGene00013530
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in regulatory ncRNA-mediated gene silencing. Predicted to be located in cytoplasm and nucleus. Predicted to be part of CCR4-NOT complex. Orthologous to human CNOT11 (CCR4-NOT transcription complex subunit 11). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ntl-11 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
11
Sequence:
Chromosome: IV; NC_003282.8 (15455127..15471494, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene PAN-3 domain-containing protein Neighboring gene General transcription factor IIH subunit 4 Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene 2Fe-2S ferredoxin-type domain-containing protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Ccr4-Not deadenylase complex constitutes the main poly(A) removal activity in C. elegans. Nousch M, et al. J Cell Sci, 2013 Sep 15. PMID 23843623
  2. LIN-41 and OMA Ribonucleoprotein Complexes Mediate a Translational Repression-to-Activation Switch Controlling Oocyte Meiotic Maturation and the Oocyte-to-Embryo Transition in Caenorhabditis elegans. Tsukamoto T, et al. Genetics, 2017 Aug. PMID 28576864, Free PMC Article
  3. A transcriptional cofactor regulatory network for the C. elegans intestine. Horowitz BB, et al. G3 (Bethesda), 2023 Jul 5. PMID 37119809, Free PMC Article
  4. SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans. Robert VJ, et al. Development, 2023 Nov 1. PMID 37818613, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in regulatory ncRNA-mediated gene silencing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of CCR4-NOT complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of CCR4-NOT complex IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
CCR4-NOT transcription complex subunit 11;Secreted protein
NP_001122830.1
  • Confirmed by transcript evidence
NP_001294106.1
  • Confirmed by transcript evidence
NP_001294107.1
  • Confirmed by transcript evidence
NP_001294108.1
  • Confirmed by transcript evidence
NP_001367046.1
  • Confirmed by transcript evidence
NP_502860.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    15455127..15471494 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001307177.4 → NP_001294106.1  CCR4-NOT transcription complex subunit 11 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294106.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A078BTL9
    Conserved Domains (1) summary
    pfam10155
    Location:427 → 555
    DUF2363; Uncharacterized conserved protein (DUF2363)

  2. NM_070459.5 → NP_502860.2  CCR4-NOT transcription complex subunit 11 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_502860.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9NA34
    Conserved Domains (1) summary
    pfam10155
    Location:427 → 555
    DUF2363; Uncharacterized conserved protein (DUF2363)

  3. NM_001307179.3 → NP_001294108.1  Secreted protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294108.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A078BPK7

  4. NM_001307178.3 → NP_001294107.1  CCR4-NOT transcription complex subunit 11 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294107.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A078BS59
    Conserved Domains (1) summary
    pfam10155
    Location:33 → 161
    DUF2363; Uncharacterized conserved protein (DUF2363)

  5. NM_001380548.1 → NP_001367046.1  CCR4-NOT transcription complex subunit 11 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8I0Y8
    Conserved Domains (1) summary
    pfam10155
    Location:110 → 238
    DUF2363; Uncharacterized conserved protein (DUF2363)

  6. NM_001129358.3 → NP_001122830.1  CCR4-NOT transcription complex subunit 11 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001122830.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A5HWB1
Nucleotide Protein
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