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F32D1.3 TPR_REGION domain-containing protein;dolichyl-phosphate-mannose--protein mannosyltransferase [ Caenorhabditis elegans ]

Gene ID: 178832, updated on 4-Jan-2025

Summary

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Official Symbol
F32D1.3
Official Full Name
TPR_REGION domain-containing protein;dolichyl-phosphate-mannose--protein mannosyltransferase
Primary source
WormBase:WBGene00017983
Locus tag
CELE_F32D1.3
See related
AllianceGenome:WB:WBGene00017983
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable mannosyltransferase activity. Predicted to be involved in protein O-linked mannosylation. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human TMTC2 (transmembrane O-mannosyltransferase targeting cadherins 2). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See F32D1.3 in Genome Data Viewer
Location:
chromosome: V
Exon count:
8
Sequence:
Chromosome: V; NC_003283.11 (4349751..4361569, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene AAA domain-containing protein;Fidgetin-like protein 1;Spastin/Vps4 C-terminal domain-containing protein Neighboring gene ATP synthase subunit epsilon, mitochondrial Neighboring gene DNA replication licensing factor MCM7 Neighboring gene ncRNA Neighboring gene Ground-like domain-containing protein Neighboring gene Activin_recp domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables dolichyl-phosphate-mannose-protein mannosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables mannosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in protein O-linked mannosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
TPR_REGION domain-containing protein;dolichyl-phosphate-mannose--protein mannosyltransferase
NP_001317807.1
  • Confirmed by transcript evidence
NP_504200.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    4349751..4361569 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_071799.5 → NP_504200.1  dolichyl-phosphate-mannose--protein mannosyltransferase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_504200.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O16296
    Conserved Domains (3) summary
    COG0457
    Location:448 → 748
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:655 → 681
    TPR; TPR repeat [structural motif]
    pfam08409
    Location:244 → 316
    DUF1736; Domain of unknown function (DUF1736)

  2. NM_001330857.3 → NP_001317807.1  TPR_REGION domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A168H4S5
    Conserved Domains (1) summary
    sd00006
    Location:7 → 37
    TPR; TPR repeat [structural motif]

RNA

  1. NR_138492.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version

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