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gon-14 HAT C-terminal dimerization domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 179052, updated on 2-Nov-2024

Summary

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Official Symbol
gon-14
Official Full Name
HAT C-terminal dimerization domain-containing protein
Primary source
WormBase:WBGene00002148
Locus tag
CELE_F44C4.4
See related
AllianceGenome:WB:WBGene00002148
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables signaling receptor binding activity. Involved in several processes, including defecation; gonad morphogenesis; and negative regulation of vulval development. Located in nucleus. Is expressed in several structures, including amphid socket cell; anal sphincter muscle; gonad; pharyngeal segment; and somatic gonad precursor. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See gon-14 in Genome Data Viewer
Location:
chromosome: V
Exon count:
14
Sequence:
Chromosome: V; NC_003283.11 (6606433..6611158, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene HoloCentric chromosome binding Protein Neighboring gene DUF4139 domain-containing protein;Protein F37C4.5;Transposase Neighboring gene Protein F37C4.5 Neighboring gene ncRNA Neighboring gene Cathepsin B-like cysteine proteinase 4 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. IRI-1, a LIN-15B homologue, interacts with inositol-1,4,5-triphosphate receptors and regulates gonadogenesis, defecation, and pharyngeal pumping in Caenorhabditis elegans. Walker DS, et al. Mol Biol Cell, 2004 Jul. PMID 15133127, Free PMC Article
  2. The sys-1 and sys-3 genes cooperate with Wnt signaling to establish the proximal-distal axis of the Caenorhabditis elegans gonad. Siegfried KR, et al. Genetics, 2004 Jan. PMID 15020416, Free PMC Article
  3. gon-14 functions with class B and class C synthetic multivulva genes to control larval growth in Caenorhabditis elegans. Chesney MA, et al. Genetics, 2006 Feb. PMID 16322520, Free PMC Article
  4. Cell-Specific mRNA Profiling of the Caenorhabditis elegans Somatic Gonadal Precursor Cells Identifies Suites of Sex-Biased and Gonad-Enriched Transcripts. Kroetz MB, et al. G3 (Bethesda), 2015 Oct 23. PMID 26497144, Free PMC Article
  5. Hermaphrodite cell-fate specification. Herman MA. WormBook, 2006 Jan 9. PMID 18050480, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. IRI-1 functions in known itr-1-mediated processes: upregulation of pharyngeal pumping in response to food and control of the defecation cycle.
    Title: IRI-1, a LIN-15B homologue, interacts with inositol-1,4,5-triphosphate receptors and regulates gonadogenesis, defecation, and pharyngeal pumping in Caenorhabditis elegans.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables signaling receptor binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in defecation IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in defecation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in gonad morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in multicellular organism growth IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in muscle contraction IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of vulval development IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of vulval development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in nematode larval development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of nematode pharyngeal pumping IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
HAT C-terminal dimerization domain-containing protein
NP_741557.2
  • Confirmed by transcript evidence
NP_741558.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    6606433..6611158 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_171476.6 → NP_741558.2  HAT C-terminal dimerization domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741558.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4PIU4
    Conserved Domains (1) summary
    pfam05699
    Location:652 → 678
    Dimer_Tnp_hAT; hAT family C-terminal dimerization region

  2. NM_171475.6 → NP_741557.2  HAT C-terminal dimerization domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741557.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2L033
    Conserved Domains (1) summary
    pfam05699
    Location:652 → 678
    Dimer_Tnp_hAT; hAT family C-terminal dimerization region
Nucleotide Protein
Heading Accession and Version

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