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K11C4.1 non-specific serine/threonine protein kinase [ Caenorhabditis elegans ]

Gene ID: 179078, updated on 2-Nov-2024

Summary

Official Symbol
K11C4.1
Official Full Name
non-specific serine/threonine protein kinase
Primary source
WormBase:WBGene00019642
Locus tag
CELE_K11C4.1
See related
AllianceGenome:WB:WBGene00019642
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Orthologous to human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See K11C4.1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
5
Sequence:
Chromosome: V; NC_003283.11 (6897000..6898497)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Progestin and adipoQ receptor family member 3-like Neighboring gene Ornithine decarboxylase Neighboring gene ncRNA

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
non-specific serine/threonine protein kinase
NP_504751.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    6897000..6898497
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072350.6NP_504751.1  non-specific serine/threonine protein kinase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_504751.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q94277
    Conserved Domains (1) summary
    cl21453
    Location:18286
    PKc_like; Protein Kinases, catalytic domain