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C05C8.5 Exonuclease domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 179116, updated on 9-Dec-2024

Summary

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Official Symbol
C05C8.5
Official Full Name
Exonuclease domain-containing protein
Primary source
WormBase:WBGene00015462
Locus tag
CELE_C05C8.5
See related
AllianceGenome:WB:WBGene00015462
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable exonuclease activity. Predicted to be involved in rRNA 3'-end processing. Predicted to be active in nucleus. Orthologous to human REXO5 (RNA exonuclease 5). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See C05C8.5 in Genome Data Viewer
Location:
chromosome: V
Exon count:
7
Sequence:
Chromosome: V; NC_003283.11 (7232673..7234826, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene peptidylprolyl isomerase Neighboring gene GEX Interacting protein Neighboring gene KRR1 small subunit processome component Neighboring gene BTB/POZ domain-containing protein 9 Neighboring gene Centriolar and ciliogenesis-associated protein hyls-1;Hydrolethalus syndrome protein 1 homolog

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables exonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables exonuclease activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in rRNA 3'-end processing IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Exonuclease domain-containing protein
NP_504838.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    7232673..7234826 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072437.8 → NP_504838.1  Exonuclease domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_504838.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O16312
    Conserved Domains (1) summary
    cd06145
    Location:222 → 372
    REX1_like; DEDDh 3'-5' exonuclease domain of RNA exonuclease 1, -3 and similar eukaryotic proteins
Nucleotide Protein
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