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F46B6.4 Hflx-type G domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 179372, updated on 4-Jan-2025

Summary

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Official Symbol
F46B6.4
Official Full Name
Hflx-type G domain-containing protein
Primary source
WormBase:WBGene00009769
Locus tag
CELE_F46B6.4
See related
AllianceGenome:WB:WBGene00009769
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable GTP binding activity and metal ion binding activity. Predicted to be involved in tRNA methylation and tRNA wobble uridine modification. Predicted to be active in mitochondrion. Orthologous to human GTPBP6 (GTP binding protein 6 (putative)). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See F46B6.4 in Genome Data Viewer
Location:
chromosome: V
Exon count:
5
Sequence:
Chromosome: V; NC_003283.11 (9777860..9779518, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene UPF0587 protein F46B6.12 Neighboring gene UPF3 domain-containing protein Neighboring gene LisH domain-containing protein Neighboring gene Tr-type G domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in tRNA methylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in tRNA wobble uridine modification IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Hflx-type G domain-containing protein
NP_001379125.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    9777860..9779518 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001392585.1 → NP_001379125.1  Hflx-type G domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q20446
    Conserved Domains (2) summary
    cd01878
    Location:204 → 397
    HflX; HflX GTPase family
    COG2262
    Location:55 → 456
    HflX; 50S ribosomal subunit-associated GTPase HflX [Translation, ribosomal structure and biogenesis]
Nucleotide Protein
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