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del-6 Amiloride-sensitive sodium channel [ Caenorhabditis elegans ]

Gene ID: 179474, updated on 4-Jan-2025

Summary

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Official Symbol
del-6
Official Full Name
Amiloride-sensitive sodium channel
Primary source
WormBase:WBGene00011891
Locus tag
CELE_T21C9.3
See related
AllianceGenome:WB:WBGene00011891
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See del-6 in Genome Data Viewer
Location:
chromosome: V
Exon count:
7
Sequence:
Chromosome: V; NC_003283.11 (10572914..10575454)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene GTP cyclohydrolase 1 Neighboring gene Vacuolar protein sorting-associated protein 54 Neighboring gene ncRNA Neighboring gene Mitochondrial scaffolding protein 1;PDZ domain-containing protein Neighboring gene Enhancer of rudimentary homolog

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Physiological insight into the conserved properties of Caenorhabditis elegans acid-sensing degenerin/epithelial sodium channels. Kaulich E, et al. J Physiol, 2023 May. PMID 36200489, Free PMC Article
  2. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ligand-gated sodium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sodium channel activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in sodium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sodium ion transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Amiloride-sensitive sodium channel
NP_001367018.1
  • Confirmed by transcript evidence
NP_741622.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    10572914..10575454
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_171534.9 → NP_741622.2  Amiloride-sensitive sodium channel [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741622.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MPW0
    Conserved Domains (1) summary
    cl02990
    Location:347 → 484
    ASC; Amiloride-sensitive sodium channel

  2. NM_001380748.1 → NP_001367018.1  Amiloride-sensitive sodium channel [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MPW1
    Conserved Domains (1) summary
    pfam00858
    Location:337 → 484
    ASC; Amiloride-sensitive sodium channel
Nucleotide Protein
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Gene LinkOut

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