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pas-2 Proteasome subunit alpha type-2 [ Caenorhabditis elegans ]

Gene ID: 179493, updated on 2-Nov-2024

Summary

Official Symbol
pas-2
Official Full Name
Proteasome subunit alpha type-2
Primary source
WormBase:WBGene00003923
Locus tag
CELE_D1054.2
See related
AllianceGenome:WB:WBGene00003923
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables identical protein binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of proteasome core complex, alpha-subunit complex. Orthologous to human PSMA2 (proteasome 20S subunit alpha 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See pas-2 in Genome Data Viewer
Location:
chromosome: V
Exon count:
4
Sequence:
Chromosome: V; NC_003283.11 (10770368..10771351)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ANK_REP_REGION domain-containing protein;Ion transport domain-containing protein Neighboring gene ncRNA Neighboring gene PNPLA domain-containing protein Neighboring gene SGS domain-containing protein Neighboring gene ncRNA Neighboring gene CBS domain-containing protein

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in proteolysis involved in protein catabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of proteasome complex IEA
Inferred from Electronic Annotation
more info
 
part_of proteasome core complex IEA
Inferred from Electronic Annotation
more info
 
part_of proteasome core complex, alpha-subunit complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of proteasome core complex, alpha-subunit complex IEA
Inferred from Electronic Annotation
more info
 
part_of proteasome core complex, alpha-subunit complex ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
Proteasome subunit alpha type-2
NP_505750.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    10770368..10771351
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_073349.9NP_505750.1  Proteasome subunit alpha type-2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505750.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q27488
    Conserved Domains (2) summary
    PRK03996
    Location:10228
    PRK03996; proteasome subunit alpha; Provisional
    cd03750
    Location:5229
    proteasome_alpha_type_2; proteasome_alpha_type_2. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on ...