U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

T19B10.5 PDZ domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 179553, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
T19B10.5
Official Full Name
PDZ domain-containing protein
Primary source
WormBase:WBGene00011833
Locus tag
CELE_T19B10.5
See related
AllianceGenome:WB:WBGene00011833
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be located in membrane and nucleus. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 3 and Charcot-Marie-Tooth disease type 4F. Orthologous to human AHNAK2 (AHNAK nucleoprotein 2) and PRX (periaxin). [provided by Alliance of Genome Resources, Dec 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See T19B10.5 in Genome Data Viewer
Location:
chromosome: V
Exon count:
7
Sequence:
Chromosome: V; NC_003283.11 (11234650..11237427)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DNA-dependent metalloprotease dvc-1 Neighboring gene ncRNA Neighboring gene Importin subunit alpha-1

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding. Lenfant N, et al. BMC Genomics, 2010 Nov 26. PMID 21110867, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
PDZ domain-containing protein
NP_505852.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    11234650..11237427
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_073451.8 → NP_505852.3  PDZ domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505852.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q22559
    Conserved Domains (2) summary
    PTZ00449
    Location:340 → 483
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    smart00228
    Location:137 → 208
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous