npp-22 Nucleoporin ndc-1 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: npp-22
Official Full Name: Nucleoporin ndc-1
Primary source: WormBase:WBGene00007118
Locus tag: CELE_B0240.4
See related: AllianceGenome:WB:WBGene00007118
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in nuclear pore organization. Part of nuclear pore. Orthologous to human NDC1 (NDC1 transmembrane nucleoporin). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See npp-22 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 8

Sequence:: Chromosome: V; NC_003283.11 (11731120..11733472, complement)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

B0240.2 (e-PCR)
- UniSTS:308834

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables protein-macromolecule adaptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in mRNA transport	IEA Inferred from Electronic Annotation more info
involved_in nuclear pore organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in nuclear membrane	IEA Inferred from Electronic Annotation more info
part_of nuclear pore	IDA Inferred from Direct Assay more info	PubMed
part_of nuclear pore	IEA Inferred from Electronic Annotation more info
part_of nuclear pore transmembrane ring	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Nucleoporin ndc-1

NP_505962.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

11731120..11733472 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_073561.8 → NP_505962.2 Nucleoporin ndc-1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_505962.2

Status: REVIEWED

UniProtKB/Swiss-Prot

Q8I4N3

Conserved Domains (1) summary

pfam09531
Location:77 → 577

Ndc1_Nup; Nucleoporin protein Ndc1-Nup