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snb-2 V-SNARE coiled-coil homology domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 179692, updated on 2-Nov-2024

Summary

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Official Symbol
snb-2
Official Full Name
V-SNARE coiled-coil homology domain-containing protein
Primary source
WormBase:WBGene00004898
Locus tag
CELE_F23H12.1
See related
AllianceGenome:WB:WBGene00004898
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable SNAP receptor activity and syntaxin binding activity. Predicted to be involved in vesicle fusion. Predicted to be located in membrane. Predicted to be part of SNARE complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome and spastic ataxia 1. Orthologous to human VAMP1 (vesicle associated membrane protein 1) and VAMP3 (vesicle associated membrane protein 3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See snb-2 in Genome Data Viewer
Location:
chromosome: V
Exon count:
3
Sequence:
Chromosome: V; NC_003283.11 (12344188..12345908, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Mitochondrial import receptor subunit TOM20 homolog Neighboring gene IncG Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Collagen triple helix repeat protein;Cuticle collagen 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables SNAP receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables syntaxin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in vesicle fusion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of SNARE complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
V-SNARE coiled-coil homology domain-containing protein
NP_506093.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    12344188..12345908 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_073692.6 → NP_506093.2  V-SNARE coiled-coil homology domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_506093.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q19767, Q7KIS0, Q9NGU4
    Conserved Domains (1) summary
    cd15870
    Location:28 → 90
    R-SNARE_VAMP2; SNARE motif of VAMP2
Nucleotide Protein
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Gene LinkOut

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