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ril-2 RNAi-Induced Longevity [ Caenorhabditis elegans ]

Gene ID: 179725, updated on 4-Jan-2025

Summary

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Official Symbol
ril-2
Official Full Name
RNAi-Induced Longevity
Primary source
WormBase:WBGene00007586
Locus tag
CELE_C14C10.3
See related
AllianceGenome:WB:WBGene00007586
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in lysosome organization and regulation of intracellular pH. Predicted to be located in membrane. Predicted to be active in lysosome. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See ril-2 in Genome Data Viewer
Location:
chromosome: V
Exon count:
7
Sequence:
Chromosome: V; NC_003283.11 (12596387..12599157, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ERAP1_C domain-containing protein Neighboring gene Leucine-rich PPR motif-containing protein, mitochondrial Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene Proteasome activator complex subunit 4 Neighboring gene ncRNA Neighboring gene putative ergosterol biosynthetic protein 28 homolog Neighboring gene Conserved secreted protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen. Hansen M, et al. PLoS Genet, 2005 Jul. PMID 16103914, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in lysosome organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of intracellular pH IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in lysosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
RNAi-Induced Longevity
NP_001023658.1
  • Product from WormBase gene class ril;
    Confirmed by transcript evidence
NP_001023659.1
  • Product from WormBase gene class ril;
    Confirmed by transcript evidence
NP_001256436.1
  • Product from WormBase gene class ril;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    12596387..12599157 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001028488.6 → NP_001023659.1  RNAi-Induced Longevity [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023659.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q52GY7

  2. NM_001269507.4 → NP_001256436.1  RNAi-Induced Longevity [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256436.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E3W740

  3. NM_001028487.8 → NP_001023658.1  RNAi-Induced Longevity [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001023658.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q17973
Nucleotide Protein
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