U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

R11D1.1 WD_REPEATS_REGION domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 179738, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
R11D1.1
Official Full Name
WD_REPEATS_REGION domain-containing protein
Primary source
WormBase:WBGene00011242
Locus tag
CELE_R11D1.1
See related
AllianceGenome:WB:WBGene00011242
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in negative regulation of fatty acid biosynthetic process. Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to human DCAF5 (DDB1 and CUL4 associated factor 5). [provided by Alliance of Genome Resources, Dec 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See R11D1.1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
9
Sequence:
Chromosome: V; NC_003283.11 (12704377..12707766)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene IST1 homolog Neighboring gene F-box domain-containing protein Neighboring gene DUF19 domain-containing protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in negative regulation of fatty acid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of Cul4-RING E3 ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
WD_REPEATS_REGION domain-containing protein
NP_001263874.1
  • Confirmed by transcript evidence
NP_001263875.1
  • Confirmed by transcript evidence
NP_001379144.1
  • Confirmed by transcript evidence
NP_506171.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    12704377..12707766
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001276945.4 → NP_001263874.1  WD_REPEATS_REGION domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001263874.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    L8EC35
    Conserved Domains (3) summary
    COG2319
    Location:39 → 399
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:69 → 111
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:58 → 395
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. NM_073770.6 → NP_506171.2  WD_REPEATS_REGION domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_506171.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q21934
    Conserved Domains (3) summary
    COG2319
    Location:39 → 399
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:69 → 111
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:58 → 395
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. NM_001392630.1 → NP_001379144.1  WD_REPEATS_REGION domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7JLF4
    Conserved Domains (2) summary
    COG2319
    Location:58 → 401
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:69 → 110
    7WD40; WD40 repeat [structural motif]

  4. NM_001276946.4 → NP_001263875.1  WD_REPEATS_REGION domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001263875.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    L8E955
    Conserved Domains (4) summary
    smart00320
    Location:357 → 394
    WD40; WD40 repeats
    COG2319
    Location:58 → 401
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:69 → 110
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:58 → 211
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous