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set-5 SET domain-containing protein;SPK domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 179973, updated on 4-Jan-2025

Summary

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Official Symbol
set-5
Official Full Name
SET domain-containing protein;SPK domain-containing protein
Primary source
WormBase:WBGene00008145
Locus tag
CELE_C47E8.8
See related
AllianceGenome:WB:WBGene00008145
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Is expressed in germ line. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See set-5 in Genome Data Viewer
Location:
chromosome: V
Exon count:
18
Sequence:
Chromosome: V; NC_003283.11 (14698966..14707601)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene Protein unc-112 Neighboring gene Uncharacterized protein Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans. Greer EL, et al. Nature, 2010 Jul 15. PMID 20555324, Free PMC Article
  2. Two C. elegans histone methyltransferases repress lin-3 EGF transcription to inhibit vulval development. Andersen EC, et al. Development, 2007 Aug. PMID 17634190
  3. Epigenetics in C. elegans: facts and challenges. Wenzel D, et al. Genesis, 2011 Aug. PMID 21538806
  4. A transcriptional cofactor regulatory network for the C. elegans intestine. Horowitz BB, et al. G3 (Bethesda), 2023 Jul 5. PMID 37119809, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

General protein information

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Preferred Names
SET domain-containing protein;SPK domain-containing protein
NP_001256612.1
  • Confirmed by transcript evidence
NP_001256613.1
  • Confirmed by transcript evidence
NP_001256614.1
  • Confirmed by transcript evidence
NP_001263889.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    14698966..14707601
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001269683.3 → NP_001256612.1  SET domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256612.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EEE4
    Conserved Domains (4) summary
    PHA03309
    Location:793 → 1008
    PHA03309; transcriptional regulator ICP4; Provisional
    smart00317
    Location:36 → 151
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    smart00583
    Location:1006 → 1118
    SPK; domain in SET and PHD domain containing proteins and protein kinases
    PTZ00108
    Location:1115 → 1328
    PTZ00108; DNA topoisomerase 2-like protein; Provisional

  2. NM_001276960.4 → NP_001263889.1  SET domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001263889.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    K8ESG9
    Conserved Domains (4) summary
    PHA03309
    Location:793 → 1008
    PHA03309; transcriptional regulator ICP4; Provisional
    smart00317
    Location:36 → 151
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    smart00583
    Location:1006 → 1118
    SPK; domain in SET and PHD domain containing proteins and protein kinases
    PTZ00108
    Location:1115 → 1330
    PTZ00108; DNA topoisomerase 2-like protein; Provisional

  3. NM_001269684.3 → NP_001256613.1  SPK domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256613.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2FLH7
    Conserved Domains (3) summary
    PHA03309
    Location:565 → 780
    PHA03309; transcriptional regulator ICP4; Provisional
    smart00583
    Location:778 → 890
    SPK; domain in SET and PHD domain containing proteins and protein kinases
    PTZ00108
    Location:887 → 1103
    PTZ00108; DNA topoisomerase 2-like protein; Provisional

  4. NM_001269685.3 → NP_001256614.1  SPK domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256614.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2FLH6
    Conserved Domains (3) summary
    PHA03309
    Location:565 → 780
    PHA03309; transcriptional regulator ICP4; Provisional
    smart00583
    Location:778 → 890
    SPK; domain in SET and PHD domain containing proteins and protein kinases
    PTZ00108
    Location:887 → 1100
    PTZ00108; DNA topoisomerase 2-like protein; Provisional
Nucleotide Protein
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