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flor-1 Protein kinase domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 180021, updated on 4-Jan-2025

Summary

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Official Symbol
flor-1
Official Full Name
Protein kinase domain-containing protein
Primary source
WormBase:WBGene00011339
Locus tag
CELE_T01G5.1
See related
AllianceGenome:WB:WBGene00011339
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in cell surface receptor protein tyrosine kinase signaling pathway. Predicted to be located in membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in hypodermis. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See flor-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
9
Sequence:
Chromosome: V; NC_003283.11 (15116844..15119617, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Secreted protein Neighboring gene Uncharacterized protein Neighboring gene UDP-glucuronosyltransferase Neighboring gene Serpentine Receptor, class J Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A PAX6-regulated receptor tyrosine kinase pairs with a pseudokinase to activate immune defense upon oomycete recognition in Caenorhabditis elegans. Drury F, et al. Proc Natl Acad Sci U S A, 2023 Sep 26. PMID 37725647, Free PMC Article
  2. Discovery of novel alternatively spliced C. elegans transcripts by computational analysis of SAGE data. Ruzanov P, et al. BMC Genomics, 2007 Nov 30. PMID 18053145, Free PMC Article
  3. Genomic overview of protein kinases. Manning G. WormBook, 2005 Dec 13. PMID 18050405, Free PMC Article
  4. A global analysis of genetic interactions in Caenorhabditis elegans. Byrne AB, et al. J Biol, 2007. PMID 17897480, Free PMC Article
  5. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane receptor protein tyrosine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in multicellular organism development IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Protein kinase domain-containing protein
NP_506728.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    15116844..15119617 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_074327.4 → NP_506728.2  Protein kinase domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_506728.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    O18008
    Conserved Domains (1) summary
    smart00221
    Location:138 → 427
    STYKc; Protein kinase; unclassified specificity
Nucleotide Protein
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