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nhr-79 Nuclear hormone receptor family member nhr-79;Nuclear receptor domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 180265, updated on 9-Dec-2024

Summary

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Official Symbol
nhr-79
Official Full Name
Nuclear hormone receptor family member nhr-79;Nuclear receptor domain-containing protein
Primary source
WormBase:WBGene00003669
Locus tag
CELE_T26H2.9
See related
AllianceGenome:WB:WBGene00003669
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in several structures, including Eala; Ealaa; Ealp; amphid neurons; and intestine. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See nhr-79 in Genome Data Viewer
Location:
chromosome: V
Exon count:
11
Sequence:
Chromosome: V; NC_003283.11 (19207676..19211895, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Serine/threonine specific protein phosphatases domain-containing protein;Serine/threonine-protein phosphatase 5 Neighboring gene Histidine-rich glycoprotein-like Neighboring gene ncRNA Neighboring gene Gustatory receptor Neighboring gene Acyl_transf_3 domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Endocrine pheromones couple fat rationing to dauer diapause through HNF4α nuclear receptors. Gao C, et al. Sci China Life Sci, 2021 Dec. PMID 34755252
  2. unc-42 regulates the expression of ASH terminal fate markers. Wood J, et al. MicroPubl Biol, 2019 May 15. PMID 32550468, Free PMC Article
  3. Nuclear receptors NHR-49 and NHR-79 promote peroxisome proliferation to compensate for aldehyde dehydrogenase deficiency in C. elegans. Zeng L, et al. PLoS Genet, 2021 Jul. PMID 34237064, Free PMC Article
  4. Coordinate regulation of lipid metabolism by novel nuclear receptor partnerships. Pathare PP, et al. PLoS Genet, 2012. PMID 22511885, Free PMC Article
  5. Systems-level transcriptional regulation of Caenorhabditis elegans metabolism. Nanda S, et al. Mol Syst Biol, 2023 May 9. PMID 36942755, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Nuclear receptors NHR-49 and NHR-79 promote peroxisome proliferation to compensate for aldehyde dehydrogenase deficiency in C. elegans.
    Title: Nuclear receptors NHR-49 and NHR-79 promote peroxisome proliferation to compensate for aldehyde dehydrogenase deficiency in C. elegans.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Nuclear hormone receptor family member nhr-79;Nuclear receptor domain-containing protein
NP_001360177.1
  • Confirmed by transcript evidence
NP_507734.4
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    19207676..19211895 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_075333.9 → NP_507734.4  Nuclear hormone receptor family member nhr-79 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_507734.4

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O18141
    UniProtKB/TrEMBL
    Q9BJK8
    Conserved Domains (2) summary
    smart00399
    Location:5 → 77
    ZnF_C4; c4 zinc finger in nuclear hormone receptors
    smart00430
    Location:253 → 429
    HOLI; Ligand binding domain of hormone receptors

  2. NM_001373193.1 → NP_001360177.1  Nuclear receptor domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    J7SF88
    Conserved Domains (1) summary
    smart00399
    Location:5 → 77
    ZnF_C4; c4 zinc finger in nuclear hormone receptors
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O18141.2

Gene LinkOut

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