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dyf-19 Fas-binding factor 1 C-terminal domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 180283, updated on 4-Jan-2025

Summary

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Official Symbol
dyf-19
Official Full Name
Fas-binding factor 1 C-terminal domain-containing protein
Primary source
WormBase:WBGene00012826
Locus tag
CELE_Y43F8C.4
See related
AllianceGenome:WB:WBGene00012826
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in non-motile cilium assembly. Located in ciliary basal body and dendrite. Is expressed in ciliated neurons. Orthologous to human FBF1 (Fas binding factor 1). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See dyf-19 in Genome Data Viewer
Location:
chromosome: V
Exon count:
11
Sequence:
Chromosome: V; NC_003283.11 (19625049..19630761)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Neuropeptide-Like Protein Neighboring gene BTB domain-containing protein Neighboring gene tRNA Neighboring gene ncRNA Neighboring gene tRNA Neighboring gene SCP domain-containing protein Neighboring gene Chromatin complexes subunit BAP18;SANT domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TALPID3 and ANKRD26 selectively orchestrate FBF1 localization and cilia gating. Yan H, et al. Nat Commun, 2020 May 4. PMID 32366837, Free PMC Article
  2. Transition fibre protein FBF1 is required for the ciliary entry of assembled intraflagellar transport complexes. Wei Q, et al. Nat Commun, 2013. PMID 24231678, Free PMC Article
  3. The hydrolethalus syndrome protein HYLS-1 regulates formation of the ciliary gate. Wei Q, et al. Nat Commun, 2016 Aug 18. PMID 27534274, Free PMC Article
  4. A WDR47 homolog facilitates ciliogenesis by modulating intraflagellar transport. Song CX, et al. J Cell Sci, 2022 Dec 15. PMID 36453135
  5. GRDN-1/Girdin regulates dendrite morphogenesis and cilium position in two specialized sensory neuron types in C. elegans. Nechipurenko I, et al. Dev Biol, 2021 Apr. PMID 33460640, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cilium assembly IEA
Inferred from Electronic Annotation
more info
  
involved_in establishment of epithelial cell polarity IEA
Inferred from Electronic Annotation
more info
  
involved_in non-motile cilium assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in centriole IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in ciliary basal body IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in ciliary basal body IDA
Inferred from Direct Assay
more info
 PubMed 
part_of ciliary transition fiber IEA
Inferred from Electronic Annotation
more info
  
located_in dendrite IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Fas-binding factor 1 C-terminal domain-containing protein
NP_507804.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    19625049..19630761
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_075403.5 → NP_507804.2  Fas-binding factor 1 C-terminal domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_507804.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9XWN2
    Conserved Domains (2) summary
    PRK12438
    Location:54 → 177
    PRK12438; hypothetical protein; Provisional
    COG1196
    Location:155 → 520
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
Nucleotide Protein
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