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ani-3 Anillin-like protein 3 [ Caenorhabditis elegans ]

Gene ID: 180291, updated on 2-Nov-2024

Summary

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Official Symbol
ani-3
Official Full Name
Anillin-like protein 3
Primary source
WormBase:WBGene00012835
Locus tag
CELE_Y43F8C.14
See related
AllianceGenome:WB:WBGene00012835
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in actomyosin contractile ring assembly; mitotic cytokinesis; and septin ring organization. Predicted to be active in actomyosin contractile ring. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 8. Orthologous to human ANLN (anillin, actin binding protein). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ani-3 in Genome Data Viewer
Location:
chromosome: V
Exon count:
10
Sequence:
Chromosome: V; NC_003283.11 (19697732..19705212)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Multidrug resistance protein mrp-7 Neighboring gene Nucleoside hydrolase Neighboring gene ncRNA Neighboring gene Serpentine receptor class gamma Neighboring gene DUF281 domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Distinct roles for two C. elegans anillins in the gonad and early embryo. Maddox AS, et al. Development, 2005 Jun. PMID 15930113
  2. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article
  3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in actomyosin contractile ring assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitotic cytokinesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in septin ring organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in actomyosin contractile ring IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Anillin-like protein 3
NP_507814.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    19697732..19705212
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_075413.5 → NP_507814.1  Anillin-like protein 3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_507814.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9XWN6
    Conserved Domains (3) summary
    cd01263
    Location:584 → 708
    PH_anillin; Anillin Pleckstrin homology (PH) domain
    pfam00169
    Location:586 → 704
    PH; PH domain
    pfam08174
    Location:407 → 552
    Anillin; Cell division protein anillin
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9XWN6.1

Gene LinkOut

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