dpy-3 Nematode cuticle collagen N-terminal domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: dpy-3
Official Full Name: Nematode cuticle collagen N-terminal domain-containing protein
Primary source: WormBase:WBGene00001065
Locus tag: CELE_EGAP7.1
See related: AllianceGenome:WB:WBGene00001065
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be a structural constituent of cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Used to study skin disease. Orthologous to human C1QTNF9 (C1q and TNF related 9); C1QTNF9B (C1q and TNF related 9B); and OTOL1 (otolin 1). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See dpy-3 in Genome Data Viewer

Location:: chromosome: X

Exon count:: 2

Sequence:: Chromosome: X; NC_003284.9 (2144605..2145647, complement)

Chromosome X - NC_003284.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

EGAP7.1 (e-PCR)
- UniSTS:309536

STS6-215 (e-PCR)
- UniSTS:242601

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables structural constituent of cuticle	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cuticle development involved in collagen and cuticulin-based cuticle molting cycle	IGI Inferred from Genetic Interaction more info	PubMed
involved_in cuticle development involved in collagen and cuticulin-based cuticle molting cycle	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of collagen trimer	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Nematode cuticle collagen N-terminal domain-containing protein

NP_508395.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003284.9 Reference assembly

Range

2144605..2145647 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_075994.7 → NP_508395.1 Nematode cuticle collagen N-terminal domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_508395.1

Status: REVIEWED

UniProtKB/TrEMBL

Q19079

Conserved Domains (1) summary

smart01088
Location:13 → 65

Col_cuticle_N; Nematode cuticle collagen N-terminal domain